skip to Main Content

About our product, Mycosinate®

Nektr Technologies have completed its Phase II Comparator clinical trial against the European market leader with outstanding results.

Nektr’s breakthrough Technology, Mycosinate® has succeeded in outperforming the European market leader by over 5x in reducing infected area of the nail.

Untitled design (49)

What is Onychomycosis?

Fungal Nail Infection or Onychomycosis is responsible for approximately 50% of all consultations for nail disorders globally. Onychomycosis has been reported as a gender and age-related disease, as it is more prevalent in males and its incidence increases with age. Its prevalence in the general population is estimated to be between 9%-and 14% in North America, and as high as 24% in Europe.  Onychomycosis has also been found to be four times more prevalent in those over the age of 60 years. Risk factors contributing to increased incidence of fungal nail infection include diabetes mellitus, peripheral arterial disease or other circulatory issues, and a weakened immune system.

Fungal nail infections may cause nails to become discoloured, thick, fragile, or cracked. The nail may also become separated from the nail bed. Onychomycosis is more common in toenails than fingernails and can spread both to the rest of the nails of the same person, as well as to other people through surface contamination.

Why Do Current Topical Antifungals Fail to Cure Onychomycosis?


How does someone get onychomycosis?

The condition is mainly caused by dermatophyte fungi such as Trichophyton rubrum and associated pathogens. The microbes will enter through small cracks in the nail or surrounding skin area and cause an infection.

How to prevent onychomycosis?

The means by which fungal nail infection can be prevented, or the spread of infection to you and others can be prevented include:

· Wash your hands and feet regularly.

· Dry your hands and feet thoroughly.

· Keep fingernails and toenails short and clean.

· Disinfect your nail clippers after every use.

· Wear appropriate footwear in swimming pool areas, locker rooms or public showers.

· Wear sweat-absorbing socks or change your socks throughout the day.

· Choose shoes made of materials that breathe.

· Discard old shoes or treat them with disinfectants or antifungal powders.

· Choose a nail salon that is licensed and sterilizes its instruments after each client.

· Don’t use nail polish or artificial nails.

How is onychomycosis diagnosed?

Fungal infections are not the only possible cause of nail problems. Other conditions can look similar to fungal nail infections. To diagnose your condition, your doctor will first examine your nails. In order to confirm the diagnosis and decide on the best treatment a small nail clipping may be taken and sent to a laboratory for analysis.

What is the treatment for onychomycosis?

Fungal nail infections can be difficult to cure, and treatment is most successful when started early and used as directed. In general, the initial treatment prescribed for a diagnosed case of onychomycosis involves use of a topical antifungal. However, currently available topical products fail to penetrate the nail structure to irradicate the infection. This results in fungal nail infections remaining active in sufferers for months and years. If symptoms persist or worsen, systemic drugs may be prescribed. While generally effective, they usually have some undesirable side effects.

Mycosinate® is a safe and effective topical solution that can penetrate the nail without side effects, resulting in the eradication of fungal nail infection and healthy nail renewal.

Inherent Flaws in Mycological Analysis - A False Indicator of Clinical Success

Phase II comparator clinical trial results below.

Figure 1: Difference between Treatment A (Mycosinate®) and Treatment B (5% Amorolfine) in percentage change in clear healthy nail area.

Figure 2: Mycosinate® average area of infection trends

Rapid improvement leads to patient satisfaction

Mycosinate® with its low molecular weight has demonstrated a very successful pathway to deliver the lethal payload to the source of the infection.

Click on the slider and drag from left to right to view the improvement after three weeks of treatment.

– Before treatment & after Three weeks treatment 

After only three weeks of treatment with Mycosinate® there is substantial improvement in the infected nail visually looking better and a reduced infected area. 

Before T=0                     After T=3 weeks

Plans for the Future

Nektr Technologies is currently seeking a licensee to commercialise Mycosinate® (A3IS) on a global basis.

Contact Us

Do you have questions about Nektr or our technology? Connect with us using the details below or get in touch by filling out the form We would be happy to answer your questions!

Nektr Technologies,
Finisklin Business & Technology Park,
Sligo, Ireland, F91 HF66
+353 71 91 43861
Send us a message

    Back To Top