Highly Potent Antimicrobial and Anti-Biofilm Effects
The sustained release of H2O2 facilitates the Broad-Spectrum Antimicrobial and Anti-Biofilm Activity. It provides sterilization and stimulates vascular endothelial growth factor production.
The high viscosity of A3IS forms a barrier between the wound and the external environment, protecting against bacteria and providing hydration. The high sugar content also provides an additional source of glucose for proliferating cellular components such.
The sustained release of H2O2 supports the removal of necrotic tissue to promote the wound healing process. Not only does dead skin inhibit the development of healthy new tissue, but it makes the affected area more susceptible to infection.
The high concentration of sugars and other solutes creates a strong osmotic gradient which causes fluid flow through the subdermal tissue flushing bacteria, debris, slough, and necrotic tissue out of the wound, and carrying nutrients.
Low pH Levels
A3IS’ lower pH reduces protease activity, increases oxygen release from haemoglobin, and stimulates the activity of macrophages and fibroblasts during the wound healing process.
A3IS has the capacity to initiate the Hormesis Effect, a biological phenomenon whereby a beneficial effect results from exposure to low doses of an agent that is toxic when given at higher doses. A3IS exposes skin to a low dose of H2O2 which causes.
The skin is the largest organ of the human body with many physiological and immunological functions. Wound infections and chronic wound management pose a significant challenge to health care systems globally, especially considering the timely threat of multi-drug resistant pathogens. A person’s skin also defines one’s physical appearance. It is therefore not surprising that significant correlations between visible dermatological skin conditions, psycho social functioning as well as quality of life exist.
With its antimicrobial and stimulatory properties, A3IS shows great promise as a potential alternative to antibiotics for the treatment of infected skin lacerations, chronic wounds and dermatological conditions.
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Finisklin Business & Technology Park,
Sligo, Ireland, F91 HF66